Clinical Trials
Advancing Animal Health with Cutting-Edge Research
Oral rapamycin for Severe Subvalvular Aortic Stenosis (SAS) in Dogs
The purpose of this study is to evaluate whether three times weekly dosing with oral rapamycin can reverse the heart muscle changes associated with subvalvular aortic stenosis (SAS) in dogs. NC State CVM study tests oral rapamycin to reverse heart changes in dogs with severe SAS. Dogs are screened (exams, tests, ECG, X-rays, echocardiograms) and assigned to low- or high-dose rapamycin or placebo, with follow-ups at 3 and 6 months.
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Feline Hypertrophic Cardiomyopathy and Immunothrombosis
NC State study explores immunothrombosis in cats with hypertrophic cardiomyopathy (HCM). It investigates platelet and neutrophil interactions, testing drugs like clopidogrel and rivaroxaban to prevent blood clots, with lab and clinical data aiming to improve treatment for this common feline heart condition.
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The HALT Study
NC State study examines the HALT Feline HCM Study, testing a new medication for cats with subclinical hypertrophic cardiomyopathy (HCM). Eligible cats (male or spayed female, ≥18 months, <15 years, ≥2.5 kg) undergo screening (echocardiograms, blood tests) and receive treatment, with follow-ups to assess heart health improvements, all at no cost to owners
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